Thrombosis model:

It has been demonstrated that virtually all clotting factors in the zebrafish genomic sequence were conserved compared to human. Compared to mammalian, zebrafish are particularly suited to thrombolytic agent screens, as these can be arrayed in multiwell plates and readily absorb small molecules, and its transparent body in early life stage makes its convenient to evaluate compound efficacy on thrombosis and blood flow. 

Hunter has developed three thrombosis models:

1. erythrocytes injury induced thrombosis,

2. abnormal platelet aggregation induced thrombosis

3. Vascular endothelium injury induced thrombosis